Faecal Occult Blood Test

Case of the Month (Emma Scurrell September 2013)

Fungal Keratitis in a dog

Corneal scrapes, a keratectomy sample and swab were submitted from a 1-year-old Border Collie, taken from a painful white corneal opacity.

 Fig 1a. Fungal hyphae (red arrow) and spore-like conidia (black arrows) are identified within the corneal scrapes.

Fig 1b. Mixed neutrophilic inflammation associated with the fungal hyphae (red arrow) is also present in the corneal scrape.

Fig 2. The keratectomy specimen similarly reveals a heavy corneal stromal infiltrate of fungal organisms (red arrows)(H&E, x 400). 

Fig 3. Fungal culture: fungal hyphae with conidiophores and conidia.

Final Diagnosis

Fungal keratitis caused by Scedosporium sp. 


The fungus was identified as Scedosporium prolificans. This is an earth-borne opportunistic fungus that is isolated in soil and water. It is an emerging cause of fungal infections and its identification is important because it is often resistent to antifungal therapy hence necessitating surgical intervention. Fungal keratitis is not uncommon in horses and human patients but is not a common diagnosis in dogs. Corneal injury and immunocompromise (e.g. secondary to long term corticosteroid use) likely predispose to the development of fungal keratitis but a history of corneal trauma/immunosuppression is not always present in reported cases. Currently, cases of Scedosporium sp keratitis have been reported in humans, chickens and dogs.

Previous Monthly Cases

Hypertensive Retinopathy January 2010
FIP in a cat - uncommon presentation February 2010
Phaeohyphomycosis    March 2010 
Scleral Rupture April 2010
Canine and feline epulides May 2010
Erythema multiforme in a labrador retreiver June 2010
Keloidal fibrosarcoma in a labrador retreiver July 2010
Cutaneous epitheliotropic lymphoma  August 2010 
Benign cutaneous histiocytoma  September 2010 
Iridociliary adenoma October 2010
Proliferative thrombovascular necrosis of the pinnae November 2010
Signet-ring cell carcinoma in the stomach of a dog December 2010
Cutaneous infiltrative lipoma in a labrador January 2011

Tonsillar squamous cell carcinoma February 2011
Canine orbital meningioma March 2011
"Lung-digit" syndrome in a cat April 2011
Hepatic amyloidosis in a cat May 2011
Haemophagocytic histiocytic sarcoma June 2011
Alternaria spp. infection in an immunocompromised dog July 2011
Ocular manifestation of lymphoma in a cat  August 2011
Kerion dermatophytosis in a Cocker spaniel September 2011
Subcuticular coenurus in a rabbit  October 2011
Optic nerve glioma in a dog November 2011
Malignant transformation of a viral papilloma in a dog  December 2011
Uveodermatological syndrome in an Akita
January 2012
Cutaneous angiostomatosis in a dog  February 2012
Transitional cell carcinoma in a dog  March 2012
Corneal inclusion cysts in a dog   April 2012
Extraskeletal osteosarcoma in a dog  May 2012
Subungual melanoma in a dog  June 2012
Retrobulbar grass seed in a dog   July 2012
Lungworm infection associated with hypercalcaemia in a dog  August 2012
Conjunctival melanoma in a dog  September 2012
Pneumocystis infection in a Cavalier King Charles Spaniel  October 2012
Fungal keratitis and secondary endophthalmitis in a horse November 2012
Myeloid leukaemia with lymph node invasion in a dog    December 2012
Cutaneous toxoplasmosis in a cat   January 2013
Glomerulonephritis in a dog  February 2013
Splenic mast cell tumour in a cat  March 2013
Laryngeal rhabdomyoma in a dog  April 2013
Mycobacterial infection in an eye May 2013
Key Gaskell syndrome in a cat June 2013
Intraosseous epidermoid cyst in the toe of a dog July 2013
Septic Lens Implantation Syndrome August 2013

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Faecal Occult Blood Test