Faecal Occult Blood Test

Case of the Month (Emma Scurrell December 2014)

Squamous cell carcinoma in the orbit of a dog

A nine-year-old male Rottweiler presented with unilateral exophthalmos and findings revealed a retrobulbar mass. Fine needle aspirates were taken from the mass and the results are shown below.

 




Fig 1.The smears are highly cellular and the cell population is well-preserved (modified Wrights-Giemsa, x40)



Fig 2. The dominant cell population consists of neoplastic squamous epithelial cells present singly and in small clusters. There is associated neutrophilic inflammation present (x200)

 

 

Fig 3. A close view of the neoplastic squamous epithelial cells (x400).
 




Final Diagnosis

Squamous cell carcinoma (SCC)

 Discussion

Squamous cell carcinomas are malignant, locally invasive neoplasms. The orbit would be a very unusual site for a primary SCC. A more common scenario is invasion of a primary sinonasal SCC through the medial orbital wall. Metastasis to the orbit from a primary SCC elsewhere is another possibility, but this is rare.

Previous Monthly Cases

Hypertensive Retinopathy January 2010
FIP in a cat - uncommon presentation February 2010
Phaeohyphomycosis    March 2010 
Scleral Rupture April 2010
Canine and feline epulides May 2010
Erythema multiforme in a labrador retreiver June 2010
Keloidal fibrosarcoma in a labrador retreiver July 2010
Cutaneous epitheliotropic lymphoma  August 2010 
Benign cutaneous histiocytoma  September 2010 
Iridociliary adenoma October 2010
Proliferative thrombovascular necrosis of the pinnae November 2010
Signet-ring cell carcinoma in the stomach of a dog December 2010
Cutaneous infiltrative lipoma in a labrador January 2011

Tonsillar squamous cell carcinoma February 2011
Canine orbital meningioma March 2011
"Lung-digit" syndrome in a cat April 2011
Hepatic amyloidosis in a cat May 2011
Haemophagocytic histiocytic sarcoma June 2011
Alternaria spp. infection in an immunocompromised dog July 2011
Ocular manifestation of lymphoma in a cat  August 2011
Kerion dermatophytosis in a Cocker spaniel September 2011
Subcuticular coenurus in a rabbit  October 2011
Optic nerve glioma in a dog November 2011
Malignant transformation of a viral papilloma in a dog  December 2011
Uveodermatological syndrome in an Akita
January 2012
Cutaneous angiostomatosis in a dog  February 2012
Transitional cell carcinoma in a dog  March 2012
Corneal inclusion cysts in a dog   April 2012
Extraskeletal osteosarcoma in a dog  May 2012
Subungual melanoma in a dog  June 2012
Retrobulbar grass seed in a dog   July 2012
Lungworm infection associated with hypercalcaemia in a dog  August 2012
Conjunctival melanoma in a dog  September 2012
Pneumocystis infection in a Cavalier King Charles Spaniel  October 2012
Fungal keratitis and secondary endophthalmitis in a horse November 2012
Myeloid leukaemia with lymph node invasion in a dog    December 2012
Cutaneous toxoplasmosis in a cat   January 2013
Glomerulonephritis in a dog  February 2013
Splenic mast cell tumour in a cat  March 2013
Laryngeal rhabdomyoma in a dog  April 2013
Mycobacterial infection in an eye May 2013
Key Gaskell syndrome in a cat June 2013
Intraosseous epidermoid cyst in the toe of a dog July 2013
Septic Lens Implantation Syndrome August 2013
Fungal Keratitis in a dog September 2013
Fatal Cowpox Infection in a Cat
October 2013
Lingual granular cell tumour in a dog November 2013
Leydig cell tumour in a dog December 2013
Urticarial allergic reaction in a dog January 2014
Conjunctival foreign body in a dog  February 2014
An enlarged sublumbar lymph node in a hypercalcaemic dog  March 2014
Perineural invasion of a carcinoma in a dog  April 2014
Intestinal pseudo-obstruction in a dog  May 2014
Sebaceous adenitis in a dog  June 2014
Ovarian teratoma  July 2014
Cutaneous cowpox virus infection in a cat  August 2014
Acute renal falure in a cat  September 2014
Azothioprine toxicity in a dog  October 2014
Neoplastic pleural effusion in a dog November 2014



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Faecal Occult Blood Test